Recent Posts - DAFNE Online

Sep 20, 2011

JayBee 587 posts

Topic: General Discussion / Smart Insulin

I do agree - it is a bit exciting and it's very valid that the dating of the article means it's going to be years off yet...

However, it was a lady I met yesterday that admitted that her son had been put on a "smart insulin from America" that was not licensed in the UK. She explained that even after 2 years he was still having trouble controlling his condition (we're talking someone aged around 23 years from what I could tell) so arrangements were made to put him on it (possibly through private care?)... and the main google search result that came up for this was the article I have posted.

I do find it very strange that there was not more information avaliable if people were being put on to it... but as I'm sure we're all aware, people do tell porkies.
I guess if we want more information, might be worth keeping an eye on the (seemingly) dedicated site http://www.smartinsulin.com/ but I dunno...

This just doesn't add up...

Edit:

Under the terms of the agreement, Merck will acquire all outstanding stock of SmartCells, Inc. In return SmartCells shareholders will receive an upfront cash payment and be eligible to receive clinical development and regulatory milestones for products resulting from the transaction for potential aggregate payments in excess of $500 million.

http://www.smartinsulin.com/news/news_main.html

Are they effectively saying that if you're a shareholder, you have access to product use?

Sep 20, 2011

novorapidboi26 1,819 posts

Topic: General Discussion / Blood Glucose diary

Its the same for me, and I believe its something to do with the site as opposed to your display settings.............

The comments field is still there, its just the end of the box is out of sight, not a big problem I suppose, maybe they could introduce a horizontal scroll bar or reduce the size of the DAFNE Tools menu on the right hand side..........

Sep 20, 2011

novorapidboi26 1,819 posts

Topic: General Discussion / hgv

In light of these proposed changes I might try and get my 7 ton license, there has been a few times were this would have come in handy...........the criteria to meet seems to be really easy, well, for me anyway............

The criteria being;

There has not been any severe hypoglycaemic event in the previous 12 months;

The driver has full hypoglycaemic awareness;

The driver must show adequate control of the condition by regular blood glucose monitoring, at least twice daily and at times relevant to driving*;

The driver must demonstrate an understanding of the risks of hypoglycaemia; and,

There are no other debarring complications of diabetes.

This is really god news actually, especially for drivers who have had to stop driving after diagnosis............probably need to be reviewed on an annual basis though, which is safe.........

Sep 19, 2011

briangildea2002 2 posts

Topic: General Discussion / hgv

Thanks for the help guys,dont think i will pursue it even with the new regulations coming in.

Sep 19, 2011

mum2westiesGill 502 posts

Topic: General Discussion / Blood Glucose diary

Hi,

Mine is the same, it only goes upto the Injection Site column

Sep 19, 2011

Alan 49 284 posts

Topic: General Discussion / Blood Glucose diary

When making entries in my online diary, I like to use the 'Multiple Entry' option, but recently I have found that the panel seems to cut off the 'Comments' column on the right.
Is this something I can fix on my PC or is it a problem with the actual online diary?

Sep 19, 2011

Alan 49 284 posts

Topic: General Discussion / hgv

There are changes being implemented in October 2011 - see http://www.diabetes.org.uk/driving

Sep 19, 2011

marke 686 posts

Topic: General Discussion / Smart Insulin

Their website says its still in pre-clincical trials ( the article referenced is from 2008 ) which means its still a long way from being released onto the market. It would be nice BUT its a long way from reality.

Sep 19, 2011

Steven 18 posts

Topic: DAFNE Online Mobile / Android app

Did this not come through?!!? Shocked

If possible please could we have BG figures within range highlighted in green, as on the website?

Thanks
Steven

Sep 19, 2011

novorapidboi26 1,819 posts

Topic: General Discussion / Getting partner involved

The general concern and interest is what sticks out for me.............well done for him.............. Smile

Sep 19, 2011

caroline15 45 posts

Topic: General Discussion / Getting partner involved

novorapidboi26 said:
Thanks...............it seems like so long ago now, loving married life though..........

So who was that conversation with?

Glad to hear it Very Happy

It was my (living apart) husband and he did come on the partners day on the Dafne course.

The ketones question was because Amy was constantly in hospital with DKA before she got her pump so he knows ketones are bad but didn't realise they tend to be with high BS Laughing

(He has MS - me too - and doesn't always remember what I tell him).

Sep 19, 2011

novorapidboi26 1,819 posts

Topic: General Discussion / hgv

as far as I am aware, any class of HGV is prohibited.........I am not familiar with classes and so on, but anything above 7 tonne and its a no no.............so I believe.........

I seen this quoted from the DVLA website..........

New applicants on insulin or existing drivers are barred in law from driving LGV (Cat C) or PCV (Cat D) vehicles from 1/4/91.

Drivers licensed before 1/4/91 on insulin are dealt with individually and licensed subject to satisfactory annual Consultant assessment.

Regulation changes in April 2001 allow â€œexceptional caseâ€ drivers to apply for or renew their entitlement to C1/C1E to drive small lorries with or without a trailer subject to meeting all â€œQualifying Conditionsâ€.

Sep 19, 2011

briangildea2002 2 posts

Topic: General Discussion / hgv

Hi guys,
Does anyone know if a diabetic is allowed an hgv class 2 licence? i am insulin dependant.

Sep 19, 2011

novorapidboi26 1,819 posts

Topic: Questions for HCPs / BG Results

Hey............

your carb counting seems to be really good so far with your porridge example..............the next step would be to consider your insulin/carb ratio...............

this is basically how many units of insulin you need to process the DAFNE standard of 1 carb portion (10grams).......

all new DAFNE students start at 1 unit for every 10 grams (1:1)..........then its test, test, test, adjust............

as i mentioned earlier, the best place to go is the Bournemouth website, its pretty much the same, all done at your own pace....then any questions you have can be asked here............have you told your team about your interest in carb counting and your intentions to delve deeper................?

Sep 19, 2011

novorapidboi26 1,819 posts

Topic: General Discussion / Getting partner involved

Thanks...............it seems like so long ago now, loving married life though..........

So who was that conversation with?

Sep 19, 2011

novorapidboi26 1,819 posts

Topic: General Discussion / Smart Insulin

Always wary of these things, but the idea is exciting I suppose......................

But it would be like having a large dose if insulin inside you just waiting to be released, which has it risks I suppose......

Sep 19, 2011

JayBee 587 posts

Topic: General Discussion / Smart Insulin

Surprised there wasn't a discussion already about this...

http://www.technologyreview.com/biomedicine/21613/?a=f

Maintaining tight control over blood-sugar levels is a daily challenge for people with diabetes: it requires constant monitoring and multiple insulin injections each day. Now the biotech company SmartCells, based in Beverly, MA, is developing a drug that may do most of the heavy lifting in controlling diabetes. The injectable drug, called SmartInsulin, senses high glucose levels and automatically dispenses insulin on demand. As glucose levels drop off, the drug stabilizes, trapping insulin until the next glucose spike. Such a drug may cut down the number of insulin injections required to once a day.

Our thoughts on this?
I'm wary myself.

Sep 19, 2011

Lizzie 87 posts

Topic: General Discussion / Can someone please remind me...

Thanks for all the helpful advice.

I thought the night hypo causing a morning high thing was a myth or misconception according to the recent post on here?

Regarding the metformin, I was on it. I stopped taking it when my prescription was cut without consultation and I kept running out before I got the next prescription. Since then my blood sugars have not really got straight again. I wish I had never taken it. I never lost any weight in fact I was gaining, and it did not improve my blood sugars. Before I took it I was just out of DAFNE, my ratios were working fine and I was losing weight. Metformin just messed everything up.

Sep 18, 2011

caroline15 45 posts

Topic: General Discussion / Getting partner involved

Haven't been on here for a while but thought I would share our conversation last week

Me: My blood's low

Him: Do you have ketones Confused

By the way many congrats on your marriage novarapidboi Very Happy

(Amy and I both on pump as of last Monday Very Happy

hope you get one soon).

Sep 18, 2011

Damo8 9 posts

Topic: General Discussion / Android App

Thanks keith, makes a lot more sense to me now.

Sep 18, 2011

KeithCl 43 posts

Topic: General Discussion / Android App

Damo8 said:
So do the calculations only count those with sa prefix rather than taking the ones marked "correctional" via the drop down?

Yes it is the + or - that is used as the indication that its a correction. Somewhere in the beta thread someone asked what the "Correctional" entry type was for and I had to answer that I did not know; the Android (and iPhone AFAIK) code does not perform any processing based on that value.

Although the Android code allows multiple entries to have the same date/time, I just tried an upload and it looks like this site does not as you discovered. So it may be that I should add some code to the phone to disallow the creation of multiple entries with the same date/time.

Sep 18, 2011

Damo8 9 posts

Topic: General Discussion / Android App

Hi guys, I had not realised that I should use plus and minus symbols. So I will start using those. So my single entry corrections were just 2 rather than + 2.

So do the calculations only count those with sa prefix rather than taking the ones marked "correctional" via the drop down?

Regarding the missing ones with the same date and time. They were saved in my phone but not on the dafne web site. Maybe an upload problem but a bit of a coincidence. I'll be adding the correction along with the other stuff more using the prefix so problem solved anyway.

Cheers.

Sep 18, 2011

mum2westiesGill 502 posts

Topic: Questions for HCPs / BG Results

Hi Dave,
Yes i have got a built in web cam and i do use skype, Could you not copy and paste your charts then either put them into a word pad or just copy and paste straight into an email. I think we can exchange email adds using the message inboox on the left hand side of here. I ordered the book "CARBS AND CALS FOR PEOPLE WITH DIABETES BY CHRIS CHEYETTE AND YELLO BALOLIA," and it arrived on Friday Very Happy

. I am becoming familiar with the fact a 1: 1 ratio means it's 1 unit of QA insulin to every 10 carbs eaten. I had porridge and 1 round of roberts thick sliced bread this morning for breakfast which looking at the photos in the carbs and cals book would be about 37cp (porridge) and 20cp bread = 57cp & i did 6u of QA humalog insulin. I saw my diabetic specialist nurse ( a new one at the gp surgery) on Thursday, she said to alter my insulin to 5-6u QA humalog from 10u, stick to 10u at lunch ( usually a sandwich / crisps / soup but not all three), 12 - 14u at dinner (spag bol, chilli, casserole...) & stick to 34u at bedtime (sometimes have supper sometimes not). Hope me dribbling on makes some sense to you, lol Laughing

Sep 18, 2011

KeithCl 43 posts

Topic: General Discussion / Android App

Damo8 said:
yes that's exactly what I meant. I see now that I've had a better look at the website itself that that's how out is in the blood glucose diary.

I just copied the diary entry layout from the iPhone app; I imagine the layout was chosen because of screen space issues, where for these mobile devices there are often only 320 pixels across compared to a computer screen that has 1024 pixels. That makes more than a few columns of output impossible to fit on the screen.

Damo8 said:

On the other point, my summary doesn't seem to be picking up anything for correctional

I'm having trouble reproducing you situation. First, the date/time is not the key so it should be possible to have multiple entries for the same date/time. I've just entered the following QA values over a couple of minutes to an empty database:

8
+2
6+1
8-1
-2

and that yields:

TDD (BI + QA) Averages/Last 7 Days: 22.0 IU
Corrective QA Counts (7/14/30/90 Days)/Before Lunch: 2+2-/2+2-/2+2-/2+2-

These results are what I would expect: the average is the sum of all the numbers (because they are all from the same day) with the corrections (indicated by the + or - prefix) added or subtracted and the correction instance counts are correct whether the correction is entered on its own (e.g. +2) or at the same time as the non corrected value (e.g. 6+1).

Please supply complete detail of what you are doing so I can reproduce the problem.

Sep 20, 2011 JayBee 587 posts	Topic: General Discussion / Smart Insulin I do agree - it is a bit exciting and it's very valid that the dating of the article means it's going to be years off yet... However, it was a lady I met yesterday that admitted that her son had been put on a "smart insulin from America" that was not licensed in the UK. She explained that even after 2 years he was still having trouble controlling his condition (we're talking someone aged around 23 years from what I could tell) so arrangements were made to put him on it (possibly through private care?)... and the main google search result that came up for this was the article I have posted. I do find it very strange that there was not more information avaliable if people were being put on to it... but as I'm sure we're all aware, people do tell porkies. I guess if we want more information, might be worth keeping an eye on the (seemingly) dedicated site http://www.smartinsulin.com/ but I dunno... This just doesn't add up... Edit: Under the terms of the agreement, Merck will acquire all outstanding stock of SmartCells, Inc. In return SmartCells shareholders will receive an upfront cash payment and be eligible to receive clinical development and regulatory milestones for products resulting from the transaction for potential aggregate payments in excess of $500 million. http://www.smartinsulin.com/news/news_main.html Are they effectively saying that if you're a shareholder, you have access to product use?

Sep 20, 2011 novorapidboi26 1,819 posts	Topic: General Discussion / Blood Glucose diary Its the same for me, and I believe its something to do with the site as opposed to your display settings............. The comments field is still there, its just the end of the box is out of sight, not a big problem I suppose, maybe they could introduce a horizontal scroll bar or reduce the size of the DAFNE Tools menu on the right hand side..........

Sep 20, 2011 novorapidboi26 1,819 posts	Topic: General Discussion / hgv In light of these proposed changes I might try and get my 7 ton license, there has been a few times were this would have come in handy...........the criteria to meet seems to be really easy, well, for me anyway............ The criteria being; There has not been any severe hypoglycaemic event in the previous 12 months; The driver has full hypoglycaemic awareness; The driver must show adequate control of the condition by regular blood glucose monitoring, at least twice daily and at times relevant to driving*; The driver must demonstrate an understanding of the risks of hypoglycaemia; and, There are no other debarring complications of diabetes. This is really god news actually, especially for drivers who have had to stop driving after diagnosis............probably need to be reviewed on an annual basis though, which is safe.........

Sep 19, 2011 briangildea2002 2 posts	Topic: General Discussion / hgv Thanks for the help guys,dont think i will pursue it even with the new regulations coming in.

Sep 19, 2011 mum2westiesGill 502 posts	Topic: General Discussion / Blood Glucose diary Hi, Mine is the same, it only goes upto the Injection Site column

Sep 19, 2011 Alan 49 284 posts	Topic: General Discussion / Blood Glucose diary When making entries in my online diary, I like to use the 'Multiple Entry' option, but recently I have found that the panel seems to cut off the 'Comments' column on the right. Is this something I can fix on my PC or is it a problem with the actual online diary?

Sep 19, 2011 Alan 49 284 posts	Topic: General Discussion / hgv There are changes being implemented in October 2011 - see http://www.diabetes.org.uk/driving

Sep 19, 2011 marke 686 posts	Topic: General Discussion / Smart Insulin Their website says its still in pre-clincical trials ( the article referenced is from 2008 ) which means its still a long way from being released onto the market. It would be nice BUT its a long way from reality.

Sep 19, 2011 Steven 18 posts	Topic: DAFNE Online Mobile / Android app Did this not come through?!!? If possible please could we have BG figures within range highlighted in green, as on the website? Thanks Steven

Sep 19, 2011 novorapidboi26 1,819 posts	Topic: General Discussion / Getting partner involved The general concern and interest is what sticks out for me.............well done for him..............

Sep 19, 2011 caroline15 45 posts	Topic: General Discussion / Getting partner involved novorapidboi26 said: Thanks...............it seems like so long ago now, loving married life though.......... So who was that conversation with? Glad to hear it It was my (living apart) husband and he did come on the partners day on the Dafne course. The ketones question was because Amy was constantly in hospital with DKA before she got her pump so he knows ketones are bad but didn't realise they tend to be with high BS (He has MS - me too - and doesn't always remember what I tell him).

Sep 19, 2011 novorapidboi26 1,819 posts	Topic: General Discussion / hgv as far as I am aware, any class of HGV is prohibited.........I am not familiar with classes and so on, but anything above 7 tonne and its a no no.............so I believe......... I seen this quoted from the DVLA website.......... New applicants on insulin or existing drivers are barred in law from driving LGV (Cat C) or PCV (Cat D) vehicles from 1/4/91. Drivers licensed before 1/4/91 on insulin are dealt with individually and licensed subject to satisfactory annual Consultant assessment. Regulation changes in April 2001 allow â€œexceptional caseâ€ drivers to apply for or renew their entitlement to C1/C1E to drive small lorries with or without a trailer subject to meeting all â€œQualifying Conditionsâ€.

Sep 19, 2011 briangildea2002 2 posts	Topic: General Discussion / hgv Hi guys, Does anyone know if a diabetic is allowed an hgv class 2 licence? i am insulin dependant.

Sep 19, 2011 novorapidboi26 1,819 posts	Topic: Questions for HCPs / BG Results Hey............ your carb counting seems to be really good so far with your porridge example..............the next step would be to consider your insulin/carb ratio............... this is basically how many units of insulin you need to process the DAFNE standard of 1 carb portion (10grams)....... all new DAFNE students start at 1 unit for every 10 grams (1:1)..........then its test, test, test, adjust............ as i mentioned earlier, the best place to go is the Bournemouth website, its pretty much the same, all done at your own pace....then any questions you have can be asked here............have you told your team about your interest in carb counting and your intentions to delve deeper................?

Sep 19, 2011 novorapidboi26 1,819 posts	Topic: General Discussion / Getting partner involved Thanks...............it seems like so long ago now, loving married life though.......... So who was that conversation with?

Sep 19, 2011 novorapidboi26 1,819 posts	Topic: General Discussion / Smart Insulin Always wary of these things, but the idea is exciting I suppose...................... But it would be like having a large dose if insulin inside you just waiting to be released, which has it risks I suppose......

Sep 19, 2011 JayBee 587 posts	Topic: General Discussion / Smart Insulin Surprised there wasn't a discussion already about this... http://www.technologyreview.com/biomedicine/21613/?a=f Maintaining tight control over blood-sugar levels is a daily challenge for people with diabetes: it requires constant monitoring and multiple insulin injections each day. Now the biotech company SmartCells, based in Beverly, MA, is developing a drug that may do most of the heavy lifting in controlling diabetes. The injectable drug, called SmartInsulin, senses high glucose levels and automatically dispenses insulin on demand. As glucose levels drop off, the drug stabilizes, trapping insulin until the next glucose spike. Such a drug may cut down the number of insulin injections required to once a day. Our thoughts on this? I'm wary myself.

Sep 19, 2011 Lizzie 87 posts	Topic: General Discussion / Can someone please remind me... Thanks for all the helpful advice. I thought the night hypo causing a morning high thing was a myth or misconception according to the recent post on here? Regarding the metformin, I was on it. I stopped taking it when my prescription was cut without consultation and I kept running out before I got the next prescription. Since then my blood sugars have not really got straight again. I wish I had never taken it. I never lost any weight in fact I was gaining, and it did not improve my blood sugars. Before I took it I was just out of DAFNE, my ratios were working fine and I was losing weight. Metformin just messed everything up.

Sep 18, 2011 caroline15 45 posts	Topic: General Discussion / Getting partner involved Haven't been on here for a while but thought I would share our conversation last week Me: My blood's low Him: Do you have ketones By the way many congrats on your marriage novarapidboi (Amy and I both on pump as of last Monday hope you get one soon).

Sep 18, 2011 Damo8 9 posts	Topic: General Discussion / Android App Thanks keith, makes a lot more sense to me now.

Sep 18, 2011 KeithCl 43 posts	Topic: General Discussion / Android App Damo8 said: So do the calculations only count those with sa prefix rather than taking the ones marked "correctional" via the drop down? Yes it is the + or - that is used as the indication that its a correction. Somewhere in the beta thread someone asked what the "Correctional" entry type was for and I had to answer that I did not know; the Android (and iPhone AFAIK) code does not perform any processing based on that value. Although the Android code allows multiple entries to have the same date/time, I just tried an upload and it looks like this site does not as you discovered. So it may be that I should add some code to the phone to disallow the creation of multiple entries with the same date/time.

Sep 18, 2011 Damo8 9 posts	Topic: General Discussion / Android App Hi guys, I had not realised that I should use plus and minus symbols. So I will start using those. So my single entry corrections were just 2 rather than + 2. So do the calculations only count those with sa prefix rather than taking the ones marked "correctional" via the drop down? Regarding the missing ones with the same date and time. They were saved in my phone but not on the dafne web site. Maybe an upload problem but a bit of a coincidence. I'll be adding the correction along with the other stuff more using the prefix so problem solved anyway. Cheers.

Sep 18, 2011 mum2westiesGill 502 posts	Topic: Questions for HCPs / BG Results Hi Dave, Yes i have got a built in web cam and i do use skype, Could you not copy and paste your charts then either put them into a word pad or just copy and paste straight into an email. I think we can exchange email adds using the message inboox on the left hand side of here. I ordered the book "CARBS AND CALS FOR PEOPLE WITH DIABETES BY CHRIS CHEYETTE AND YELLO BALOLIA," and it arrived on Friday . I am becoming familiar with the fact a 1: 1 ratio means it's 1 unit of QA insulin to every 10 carbs eaten. I had porridge and 1 round of roberts thick sliced bread this morning for breakfast which looking at the photos in the carbs and cals book would be about 37cp (porridge) and 20cp bread = 57cp & i did 6u of QA humalog insulin. I saw my diabetic specialist nurse ( a new one at the gp surgery) on Thursday, she said to alter my insulin to 5-6u QA humalog from 10u, stick to 10u at lunch ( usually a sandwich / crisps / soup but not all three), 12 - 14u at dinner (spag bol, chilli, casserole...) & stick to 34u at bedtime (sometimes have supper sometimes not). Hope me dribbling on makes some sense to you, lol

Sep 18, 2011 KeithCl 43 posts	Topic: General Discussion / Android App Damo8 said: yes that's exactly what I meant. I see now that I've had a better look at the website itself that that's how out is in the blood glucose diary. I just copied the diary entry layout from the iPhone app; I imagine the layout was chosen because of screen space issues, where for these mobile devices there are often only 320 pixels across compared to a computer screen that has 1024 pixels. That makes more than a few columns of output impossible to fit on the screen. Damo8 said: On the other point, my summary doesn't seem to be picking up anything for correctional I'm having trouble reproducing you situation. First, the date/time is not the key so it should be possible to have multiple entries for the same date/time. I've just entered the following QA values over a couple of minutes to an empty database: 8 +2 6+1 8-1 -2 and that yields: TDD (BI + QA) Averages/Last 7 Days: 22.0 IU Corrective QA Counts (7/14/30/90 Days)/Before Lunch: 2+2-/2+2-/2+2-/2+2- These results are what I would expect: the average is the sum of all the numbers (because they are all from the same day) with the corrections (indicated by the + or - prefix) added or subtracted and the correction instance counts are correct whether the correction is entered on its own (e.g. +2) or at the same time as the non corrected value (e.g. 6+1). Please supply complete detail of what you are doing so I can reproduce the problem.