Higher CP value meal - Should higher than normal QA doses be split?

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SA2010 DAFNE Graduate
University College London Hospitals (UCLH)
69 posts
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I have mentioned before that maybe QA:CP ratios break down at certain levels of CPs. Or may be when the QA dose is high (relative to the normal dose) it acts much faster than the CPs ??

I have just had an unexpected drop in BG to 3.7 mmol/l just over an hour after dinner. The only differences about this meal and QA dose from my norm were:

* Time since previous meal and QA dose was 5 hours exactly (I normally have more than 5 hour break - to be 100% sure no residual QA still in action)

* The QA dose was over 10u. My normal QA dose for dinner is between 7u and 9u most of the time.

I cannot this time say it was the cycling in the afternoon - because I had such activity on the previous 2 days and the issue did not arise then,

I am wondering now that a QA dose of 10.5u (10u+0.5u correction) for me has dropped the BG faster than the 11 CPs I had for dinner. Previous evening's meal was 9.5 CPs wih QA of 8.5u. Similar meal - difference was today there was 1 CP of Quince Paste/Jelly and 1.5 CPs of Oatcakes compared to 1 CP of Blueberry pancake yesterday. Rest of the meal the same as yesterday.

Please have a look at the diary and tell me what you think

BI = Lantus, QA = Novorapid

Thanks

Edit: Added bedtime BG to diary. 14.7 mmol/l Repeated the test and it was 15.1 in the other hand !!!!

My theory now is that the 10.5u QA at 19:00 went woosh and got all used up within the first 2 hours leaving the CPs with no QA left. There is no other explanation. Fault in Novorapid action? Known issue? Can happen??

Despite DAFNE rules I have applied some QA correction at bedtime. Only 1u - surely DAFNE rules on correction on spike after hypo needs to have some limits.

youone DAFNE Graduate
Hull University Teaching Hospitals NHS Trust
102 posts

Hi
I've posted on this subject , briefly I found that when I took more than 10u of QA my body didn't seem to use it, I never looked at the detail why.
I moved to splitting any large CP meal by 3. The last being the correction if needed, my BG would level off at My target after 4 to 5 hours after the last injection, but what was more important to me, I didn't' have lows or highs the following day.
Before Dafne I had large CP meals but only a few. After Dafne I'm having up to 20 + CP meals all the time with good target hits, also since I started running again the control is even better with my insulin amounts only a 1/3 of what there where before Dafne
So for me splitting the QA works.

Type 1 42 yrs

SA2010 DAFNE Graduate
University College London Hospitals (UCLH)
69 posts

Thanks youone for that. I have now read through the related topic "Dealing with large carb meals" and see that you and Warwick split the dose. I will now try to restrict the CPs in my meals so that I do not exceed 10u of QA or split. I also agree with comments made on that thread about getting misleading measure of BG if done after 2 hours of QA Novorapid dose - I do not measure again unless 5 hours elapsed unless I am feeling hypo coming on or sometimes a spike in BG 1-2 hours after some meals.

If I split I would do the second dose based on the initial BG pre meal measurement and the CPs for the meal rather than measure again again - leaving a correction to the measurement 5 hours after the meal. But this would lead to a potential problem for me - as to get any real accurate BG measurement I find i have to wait for 5 hours to pass after a QA dose. It is bad enough at the moment having to stay awake till 1am to do that. So I don't know... Probably better option is to keep my evening meals at 11 CPs max (I am on a QA:CP ratio for evening meal of 0.9:1)

youone DAFNE Graduate
Hull University Teaching Hospitals NHS Trust
102 posts

Hi
I note your remarks.
I had a MacDonald's meal on Saturday which was 20cp
By BG was 8.2 before meal at 6pm
I took 10mmol at the start of meal and another at 7pm
I peaked 90mins later at 11.4
At 11pm I was 7.4
In the ,morning at 5.30am I was 7.2
In this case no correction was needed because it stated on their site the meal was 20cp
So I could match close With the QA.
I think large carb meals are OK if you've got a ture CP amount to match too

Type1 42 yrs

SA2010 DAFNE Graduate
University College London Hospitals (UCLH)
69 posts

That is very good.

I would be happy with 2nd QA dose being no more than an hour after the first - I would still be ok with my personal 5 hour rule for measuring BG not before 5 hours elapsed after a QA dose.

I will try and do that - With this I can go to a Pizza Express again and eat a whole Pizza !

Thanks

youone DAFNE Graduate
Hull University Teaching Hospitals NHS Trust
102 posts

SA2010 said:
That is very good.

I would be happy with 2nd QA dose being no more than an hour after the first - I would still be ok with my personal 5 hour rule for measuring BG not before 5 hours elapsed after a QA dose.

I will try and do that - With this I can go to a Pizza Express again and eat a whole Pizza !

Thanks



Hi
I think the last time I was at pizza express a full 12 inch was 150g of carbs according to the manager, in fact he said all their pizzas are 150g
In this case you could try two options
1 x 8 + 7 1 hour later
Or
1 x 10 + ? If like me you decide to have a Pud
Hope you have a good meal
Regards
Brian
Type 1 42 yrs

paulj DAFNE Graduate
Northumbria Healthcare Trust
36 posts

I think after reading the above comments it is whatever works for that individual. I have just had my tea which consisted of a frozen pizza and a magnum ice cream. I find that when I eat a pizza I have to increase my ratio from one and a half to one and two thirds because if I don't the next morning I am normally higher than usual.my total q/a dose for the above was 21.5 units of which I took all at once. rightly or wrongly I don't concern myself with my bedtime bg reading because 5 hours have not elapsed by then i.e. if it is to high.it is the breakfast bg reading that I tend to refer to.as we all realise DAFNE is great because it gives us more freedom to eat what we want. for me personally by splitting q/a doses for large cp meals just makes the whole thing a bit more complicated and its not easy to get right at the best of times. Very Happy I remember a old saying from my previous job

K.I.S.S.-KEEP IT SIMPLEY SIMPLE

SA2010 DAFNE Graduate
University College London Hospitals (UCLH)
69 posts

I don't know - i will reserve judgement on this Paul.

I do know though that I am very sensitive to small changes in insulin dose - 1u out and there is an impact - so I would never dream of injecting 21u - anyway not with my current insulin sensitivity and to just go to bed without measuring - at the moment I do not risk that - whilst I am still able to stay awake 5 hours after dinner, Maybe when I get older I will not be able to do that but now i can and I am doing it,. By the way the 5 hours went past 2 and half hours ago - i just carried away doing things ! But definitely going to bed now

Biggest fear is getting a hypo whilst a sleep so I make sure I am close to 8.0mmol/l before bedtime (for me 7.0 to 8.5 at bed time I take no action for)

Obviously I am not benefiting from all the freedoms following DAFNE but what is the point in doing a bedtiime measure when the QA is still working and active,